Talk Python To Me

By Michael Kennedy

Talk Python to Me is a weekly podcast hosted by developer and entrepreneur Michael Kennedy. We dive deep into the popular packages and software developers, data scientists, and incredible hobbyists doing amazing things with Python. If you're new to Python, you'll quickly learn the ins and outs of the community by hearing from the leaders. And if you've been Pythoning for years, you'll learn about your favorite packages and the hot new ones coming out of open source.

9 episodes

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All Episodes

PyView: Python-Centric Real-Time Web Applications Via LiveView Protocol

Jan 23, 2026

Build real-time, interactive Python web apps without complex JavaScript. PyView leverages server-side state management and efficient updates for dynamic UIs, simplifying development.

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DiskCache: Persistent, Cross-Process Caching for Python Applications

Jan 13, 2026

Accelerate Python apps by persisting expensive computations to disk. DiskCache rivals network caches like Redis for local speed, reducing redundant operations and cloud costs.

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Python Web Deployment: Performance, Concurrency, and Framework Trade-offs

Jan 05, 2026

Upgrade Python versions for nearly double performance; leverage background tasks and optimize database indexing to boost responsiveness and efficiency.

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Python's 2025: Concurrency, Tooling, AI, and Funding Challenges

Dec 29, 2025

Python's future accelerates with the impending GIL removal and advanced tooling, promising 10x performance gains and simplified development, while the community navigates AI's impact and funding challenges.

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Right-Sized Python Deployment: Autonomy, Cost-Effectiveness, and Simpler Infrastructure

Dec 18, 2025

Deploy Python applications with right-sized engineering to cut cloud costs and complexity. Gain autonomy and simpler infrastructure management by running on a single server with Docker isolation.

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Standardizing Interactive Python Widgets With "Just Enough JavaScript"

Dec 13, 2025

Democratize interactive Python notebooks with "just enough JavaScript" for seamless, bidirectional data exploration across any environment.

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Demystifying Computing Through Building Interpreters and Emulators

Dec 03, 2025

Demystify programming by building interpreters and emulators. Discover how minimal syntax solves complex problems and understand the software-hardware interface, fostering adaptable problem-solving skills.

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Treating LLMs as APIs Requires Defensive Programming and Structured Output

Nov 30, 2025

Treat LLMs as programmable APIs, not black boxes. Implement defensive programming with caching and structured outputs to manage unpredictability and ensure data integrity.

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Model Context Protocol: Universal Interface for Agentic AI Integration

Nov 10, 2025

Connect any AI to any application or data with a universal interface, enabling dynamic, real-world interactions and composable agentic workflows beyond static training.

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