From Prostate Failure to Non-Invasive Cancer Robotics
Related Episodes
Bloom Money: Digitizing Ancient Trust for Immigrant Finance
Bloom Money digitizes ancient ROSCAs, building trust and financial inclusion for immigrants by transforming informal social capital into a powerful, data-driven credit foundation.
View Episode Notes →
Letting Go: Bottled Riddles and Parental Possessions
Unresolved regret surfaces when we can't let go of possessions, memories, or control, but external validation and mortality's shadow can force profound change and acceptance.
View Episode Notes →
Design for Actual Play--Not Theoretical Ideals
Design games and policies for how people *actually* play and live, not theoretical ideals, to ensure engagement and prevent unintended consequences.
View Episode Notes →
Kyoto's Climate Battle: Doubt, Heroes, and Enduring Lessons
Lobbyists waged war, island nations pleaded for survival, and a surprising hero emerged from the dramatic Kyoto climate negotiations, defining global climate politics.
View Episode Notes →
Shadow Banking's Rise: Lessons from 2008's Debt Crisis
Fifteen years after 2008, risk-taking prestige migrated from banks to hedge funds, while Bitcoin emerged as a critique of the system's inherent instability.
View Episode Notes →
Edison's Invention Factory: Industrializing Genius
Thomas Edison didn't just invent devices; he industrialized innovation, transforming invention into a systematic process that reshaped modern research and development.
View Episode Notes →Resources
Resources & Recommendations
Podcasts
- Business History (Hosted by Jacob Goldstein) - A new podcast about the history of business, with its first episode focusing on Southwest Airlines and an upcoming series on Thomas Edison.
- Broken Record (Hosted by Justin Richmond) - A podcast mentioned in the context of holiday music and Starbucks.
- Silver Linings with The Old Gays (Hosted by Jesse, Bill, Robert, and Mick, in partnership with iHeart's Ruby Studio and Vive Healthcare) - A bonus episode discussed in the context of uplifting the spirit of Pride.
People Mentioned
- Donny Hathaway - Referenced as a musician whose voice might evoke holiday feelings.
- Mariah Carey - Referenced as a musician whose voice might evoke holiday feelings.
- Mike Blue (CEO of HistoSonics) - The guest of the episode, discussing his company's technology.
- Dr. Fred Moll (Co-founder of Intuitive Surgical) - Described as the "godfather of robotic surgery" and an investor in HistoSonics, understanding both robotics and the histotripsy therapy.
- Trina Minino (Producer of "What's Your Problem?") - Producer of the podcast.
- Gabriel Hunter Chang (Producer of "What's Your Problem?") - Producer of the podcast.
- Alexander Gaton (Editor of "What's Your Problem?") - Editor of the podcast.
- Sarah Brier (Engineer of "What's Your Problem?") - Engineer of the podcast.
- Ryan Reynolds - Mentioned in an advertisement.
Organizations & Institutions
- Johnson & Johnson - Mike Blue's previous employer where he was a Vice President of Sales.
- University of Michigan - Where the histotripsy technology was developed and with whom HistoSonics maintains an ongoing research relationship.
- FDA (Food and Drug Administration) - The regulatory body that cleared the HistoSonics device for use in treating liver tumors and collaborated on clinical trial design.
- Intuitive Surgical - A company co-founded by Dr. Fred Moll, described as a model company for robotic surgery.
- Cleveland Clinic - The first institution to purchase and use the Edison system from HistoSonics for liver tumor patients.
- HistoSonics - The company led by Mike Blue, developing and commercializing histotripsy technology.
Research & Studies
- HOPE for Liver Study - The pivotal clinical study conducted by HistoSonics for FDA clearance, focusing on the safe and effective destruction of liver tumors in advanced-stage patients.
Tools & Software
- Edison System - The commercialized device developed by HistoSonics that uses histotripsy technology to destroy tumors. It features a large robotic arm, a 42-inch high-fidelity touchscreen display, and an ultrasound cart-like structure.